Muhammet Karaman PhD.


27. Kizilbay, G. and Karaman, M.* Possible inhibition mechanism of dobutamine hydrochloride as potent inhibitor for human glucose-6-phosphate dehydrogenase enzyme. Journal of Biomolecular Structure and Dynamics, 2021, Available Online, Article in Press.

26. Turkan, F., Calimli, M. H., Kanberoğlu, G. S., and Karaman M. Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on Glutathione S-transferase, Cholinesterases enzymes and molecular docking studies. Journal of Biomolecular Structure and Dynamics, 2021Available Online, Article in Press.

25. Tokali, F.S., Taslimi, P., Usanmaz, H., Karaman, M. Sendil, K. Synthesis, Characterization, Biological Activity and Molecular Docking Studies of Novel Schiff Bases Derived from Thiosemicarbazide: Biochemical and Computational Approach. Journal of Molecular Structure, 2021, Available Online, 


24. Tokali, F.S., Taslimi, P., Demircioglu, I.H., Karaman, M., Gultekin, M.S., Sendil, K., Gulcin, I. Design, synthesis, molecular docking, and some metabolic enzyme inhibition properties of novel quinazolinone derivativesArchiv der Pharmazie, 2021, e2000455.

23. Guller, P., Karaman, M., Guller, U., Aksoy, M., and Kufrevioglu, O.I. A study on the Effects of Inhibition Mechanism of Curcumin, Quercetin, and Resveratrol on Human Glutathione Reductase through In Vitro and In Silico ApproachesJournal of Biomolecular Structure and Dynamics, 2021Available Online, Article in Press.

22Kalin, R., Köksal, Z., Bayrak, S., Gerni, S., Ozyürek, I.N., Usanmaz, H., Karaman, M.Atasever, A., Özdemir, H., Gülçin, I. Molecular docking and inhibition profiles of some antibiotics on lactoperoxidase enzyme purified from bovine milkJournal of Biomolecular Structure and Dynamics, 2021, Available Online, Article in Press.




21. Alım, Z., Köksal, Z., Karaman, M. Evaluation of some thiophene-based sulfonamides as potent inhibitors of carbonic anhydrase I and II isoenzymes isolated from human erythrocytesby kinetic and molecular modelling studiesPharmacological Reports, 202072(6) 1738-1748.


20. Celik, H., Kucukler, S., Comakli, S., Cağlayan, C., Ozdemir, S., Yıldırm, A., Karaman, M., Handemir, F.M. Neuroprotective effect of chrysin on isoniazid-induced neurotoxicity via suppression of oxidative stress, inflammation and apoptosis in rats. NeuroToxicology2020, 81, 197-208.

19. Karaman, M., Temel, Y., Bayindir, S. Inhibition effect of rhodanines containing benzene moieties on pentose phosphate pathway enzymes and molecular dockingJournal of Molecular Structure, 2020, 1220, 128700.

18. Suayev, A., Taslimi P., Garibov, E., Karaman, M.*, Zangeneh, M.M. Novel Cyclic Thiourea Derivatives of Aminoalcohols at the Presence of AlCl3 Catalyst as Potent α-Glycosidase and α-Amylase Inhibitors: Synthesis, Characterization. Bioactivity Investigation and Molecular Docking Studies. Bioorganic Chemistry, 2020104, 104216.

17. Unluer, D., Unver, Y., Bektas, E., Direkel, S., Karaman, M., Karaman, H.S. Synthesis, Biological Activities and Molecular Docking Studies of New Schiff Bases Derivatives. Gümüşhane University Journal of Science and Technology Institute, 2020, 10(3), 681 - 694.

16. Taslimi, P., Sujayev, A., Karaman, M., Maharramova, G., Sadeghian, N., Osmanova, S.,Sardarova, S., Majdi, N., Ozel, H.U., Gulcin, I. N‐Substituted pyrimidinethione and acetophenone derivatives as a new therapeutic approach in diabetes. Archiv der Pharmazie, 2020, 353(9)e2000075.

15. Karaman, M. Pharmacophore Analyses of SARS-CoV-2 Active Main Protease Inhibitors Using Pharmacophore Query and Docking Study. ChemRxiv, 2020Available Online.

14. Ulu, A., Karaman, M., Yapıcı, F., Naz, M., Sayın, S., Saygılı, E.I., and Ateş, B. The Carboxylated Multi-walled Carbon Nanotubes/l-Asparaginase Doped Calcium-Alginate Beads: Structural and Biocatalytic Characterization. Catalysis Letters, 2020, 150,1679–1691.

14. Burmaoglu, S., Kazancioglu, E. A., Kaya, R., Kazancioglu, M., Karaman, M., Algul, O., Gulcin, I.  Synthesis of novel organohalogen chalcone derivatives and screening of their molecular docking study and some enzymes inhibition effects. Journal of Molecular Structure, 2020, 1208: 127868.

13. Yigit, M. Yigit, B., Taslimi, P., Özdemir, I., Karaman, M.Gulçin, I. Novel Amine-Functionalized Benzimidazolium Salts: Synthesis, Characterization, Bioactivity, and Molecular Docking StudiesJournal of Molecular Structure, 2020, 1207:127802.

12. Koksal, Z., Kalin, R., Kalin, P., Karaman, M., Gulcin, I., and Ozdemir, H. Lactoperoxidase inhibition of some natural phenolic compounds: Kinetics and molecular docking studies. Journal of Food Biochemistry, 2020, 44 (2):e13132.

12. Aksoy, M., Karaman, M., Guller, P., Guller, U., and Kufrevioglu, O.I. In Vitro Inhibition Effect and Molecular Docking Study of Curcumin, Resveratrol, and Quercetin on Human Erythrocyte Glutathione TransferaseCurrent Enzyme Inhibition2020, 15(3):197 - 205.

9. Bal, S., Kaya, R., Gok, Y., Taslimi, P., Aktaş, A., Karaman, M., and Gulcin, I. Novel 2-methylimidazolium Salts: Synthesis, Characterization, Molecular Docking, and Carbonic Anhydrase and Acetylcholinesterase Inhibitory Properties. Bioorganic Chemistry, 2020, 94,103468.

8. Kalin, R., Koksal, Z., Kalin, P., Karaman, M., Gulcin, I., and Ozdemir, H. In vitro effects of standard antioxidants on lactoperoxidase enzyme–A molecular docking approach. The Journal of Biochemical and Molecular Toxicology2020 34(1),e22421.

7. Taslimi, P., Turkan, F., Cetin, A., Burhan, H., Karaman, M., Bildirici, I., Gulcin, I., Sen, F. Pyrazole[3,4–d]pyridazine Derivatives: Molecular Docking and Explore of Acetylcholinesterase and Carbonic Anhydrase Enzymes Inhibitors as Anticholinergics Potentials. Bioorganic Chemistry, 2019, 92, 103213.

6. Bayindir, S., Caglayan, C., Karaman, M. and Gülcin, I. The green synthesis and molecular docking of novel N-substituted rhodanines as effective inhibitors for carbonic anhydrase and acetylcholinesterase enzymesBioorganic Chemistry, 2019, 90, 103096. 

5. Turkan, F., Cetin, A., Taslimi, P., Karaman, M., and Gulçin, I. Synthesis, biological evaluation and molecular docking of novel pyrazole derivatives as potent carbonic anhydrase and acetylcholinesterase inhibitors. Bioorganic Chemistry, 2019, 86:420-427.

4. Yigit, B., Kaya, R., Taslimi, P., Isik, I., Karaman, M., Yigit, M., Özdemir, I., and Gulçin, I. Imidazolinium chloride salts bearing wing tip groups: Synthesis, molecular docking and metabolic enzymes inhibition. Journal of Molecular Structure, 2019, 1179:709-718.


3. Karaman, M., Budak, H. Ciftci, M. Amoxicillin and Gentamicin antibiotics treatment adversely influence the fertility and morphology through decreasing the Dazl gene expression level and increasing the oxidative stress. Archives Of Physiology And Biochemistry, 2019, 125(5), 447-455.

2. Canturk, F., Karaman, M., Selby, C. P., Kemp, M. G., Kulaksiz-Erkmen, G., Hu, J., Li, W., Lindsey-Boltz, L. A. and Sancar, A. Nucleotide Excision Repair by Dual Incisions in Plants. Proceedings of the National Academy of Sciences, 2016, 113(17): 4706-10.

1. Karaman, M., Akkemik, E., Budak, H. and Ciftci, M. In Vitro Effects of Some Drugs on Human Erythrocyte Glutathione Reductase. Journal of Enzyme İnhibition and Medicinal Chemistry, 2012, 27(1): 18;23.


Book/Book Chapter

1. Cetinkaya, H., Kulak, M., Karaman, M., Karaman H. S. and Kocer, F. Book title: FLAVONOİDS-FROM BİOSYNTHESİS TO HUMAN HEALTH, Chapter title: Flavonoid accumulation behavior in response to the abiotic stress: Can a uniform mechanism be illustrated for all plants? 2017. ISBN 978-953-51-5338-2.

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