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Projects

Our Research Projects

  1. Development of new indoleamide chemosensitizer drugs by targeting nucleotide excision repair mechanism to enhance the efficiency of platinum-based chemotherapy agents on cancer treatment. Health Institutes of Turkey (TÜSEB), Project number: 2019-YI-01-288, 2021-2023. Budget: 2.375.558,89 TL.

  2. Determination of Chemotherapeutic and Chemosensitizer Properties of a New Class of Schiff Base Derivatives with Methoxy Indole-Quinazolinone Skeleton on Cancer Cells via Pentose Phosphate Pathway Inhibition Using Nano-Flower Drug Delivery Systems. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 123Z757. 15.12.2024-15.12.2026. Budget: 1.460.000,00 TL.

  3. Determination of Anti-Cancer and Chemosensitizer Activities of Bidentate Schiff Some Derivative Molecules for Lung Cancer Treatment via Pentose Phosphate Pathway Inhibition. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 120Z864. 2021-2022. Budget; 44.994,00 TL.

  4. Synthesis of Schiff Base Derivatives and detection of effect on Pentose Phosphate Pathway. The Scientific and Technological Research Council of Turkey (TÜBİTAK) and Kilis 7 Aralik University, Scientific Research Unit (BAP). 2021-2022

  5. Identification of the Effects of Anti-Arrhythmic Drugs on Human Glucose 6-Phosphate Dehydrogenase Enzyme and revelation of Their Inhibition Mechanism. Project manager. Kilis 7 Aralik University, Scientific Research Unit (BAP). 2019-2020.

  6. Investigation of the Effects of New Naphthylamide Derivatives on the Glutathione Reductase Enzyme Activity Isolated from Human Erythrocyte. Project manager. Kilis 7 Aralik University, Scientific Research Unit (BAP). 2017-2019.

Collaborative Research Projects

  1. Green Synthesis of Undoped and Al Doped ZnO Nanoparticles Using Hypericum Capitatum Flower Extract: Characterization, Anti-Quorum Sensing, Anti-Cancer and Photocatalytic Activity. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 223Z255. 15.04.2024 - 15.10.2026. Budget; 1.533.662,60TL.

  2. Synthesis of Thioredoxin Reductase 1-Targeted New Vulpinic Acid Derivatives and Investigation of Their Anticancer Effects on Breast, Lung and Liver Cancer Cell Lines. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 123Z276. 2023- . Budget; 1.200.000,00 TL.

  3. Targeting the Pentose Phosphate Pathway through Inhibition of the G6PD Enzyme Using a Novel Class of Isopropyl-Quinazolinone–Derived Schiff Base Compounds and Evaluation of Their Anticancer and Chemosensitizing Properties for Cancer Therapy. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 124C289. 202-2027. Budget; 150.000,00 TL.

  4. Synthesis of Novel 4-Methoxyphenyl-Based 4-Aminoquinazoline Derivatives and Evaluation of Their Anticancer and Chemosensitizing Properties through Inhibition of the Pentose Phosphate Pathway. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 124C111. 202-2027. Budget; 150.000,00 TL.

  5. Attachment of curcumin and cis-platinum complex to the new mesoporous Fe3O4 magnetic support, biodegradable encapsulation and determination of the effect of cis-platinum transported to the cells via the synthesized nanocarrier on death pathways in the A549 cell line by Western Blot. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project number: 121C393. 2022-2025. Budget; 113.988,00 TL.

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